약학대학 - 약학대학
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- 031-290-7784
- jlee0610@skku.edu
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관심분야
Discovery of biomarkers and understanding of molecular mechanisms of diseases and drugs through metabolomics-based studies Chromatography-based analysis of endogenous and exogenous small molecules (metabolites, drugs, and biologically active substances) in various types of matrices Development/design of green solvents (deep eutectic solvents) and their applications Statistics-based design of experiment (DoE) for efficient experiment performance Development of green sample preparation methods
학력
- (Ph.D.) University of Texas Southwestern Medical Center (Molecular Biophysics; 2008)
약력/경력
- Assistant Professor at Sungkyunkwan University (2010-Present)
- Postdoctoral Researcher at UT Southwestern Medical Center (2008-2009)
- Research Assistant at Seoul National University (1998-2000)
학술지 논문
- (2024) Green and efficient method to acquire high-value phycobiliprotein from microalgal biomass involving deep eutectic solvent-based ultrasound-assisted extraction. FOOD CHEMISTRY. 449, 1
- (2024) Fabrication of chitin-glucan nanofibers: Insights into mushroom pretreatment and subsequent acidic deep eutectic solvent-based esterification. CARBOHYDRATE POLYMERS. 323, 121391
- (2022) Ecofriendly and enhanced biogenic synthesis of silver nanoparticles using deep eutectic solvent-based green tea extracts. JOURNAL OF CLEANER PRODUCTION. 379, 134655
- (2021) Insights into the enhanced thermal stability of lysozyme with altered structure and activity induced by choline chloride-based deep eutectic solvents containing polyols and sugars. JOURNAL OF MOLECULAR LIQUIDS. 349, 118143
- (2021) Carvone and its eutectic mixtures as novel, biodegradable, and tunable solvents to extract hydrophobic compounds in substitution for volatile toxic solvents. FOOD CHEMISTRY. 374, 131630
- (2021) A solvent-free headspace GC/MS method for sensitive screening of N-nitrosodimethylamine in drug products. ANALYTICAL METHODS. 13, 30
- (2021) Preparation and characterization of various chitin-glucan complexes derived from white button mushroom using a deep eutectic solvent-based ecofriendly method. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 169, 00
- (2021) Toxico-metabolomics study of a deep eutectic solvent comprising choline chloride and urea suggests in vivo toxicity involving oxidative stress and ammonia stress. GREEN CHEMISTRY. 23, 3
- (2020) Applications of deep eutectic solvents to quantitative analyses of pharmaceuticals and pesticides in various matrices: a brief review. ARCHIVES OF PHARMACAL RESEARCH. 43, 9
- (2020) Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance. BIOMATERIALS. 262,
- (2020) Insights into the Vastly Different Effects of Eutectic Solvents on the Stability of Phenolic Compounds. JOURNAL OF PHYSICAL CHEMISTRY LETTERS. 11, 13
- (2020) In situ situ formation of thymol-based hydrophobic deep eutectic solvents: Application to antibiotics analysis in surface water based on liquid-liquid microextraction followed by liquid chromatography. JOURNAL OF CHROMATOGRAPHY A. 1614, -
- (2020) Mixing of menthol-based hydrophobic deep eutectic solvents as a novel method to tune their properties. JOURNAL OF MOLECULAR LIQUIDS. 301, -
- (2020) Systematic investigation of the extractive desulfurization of fuel using deep eutectic solvents from multifarious aspects. FUEL. 264, 1
- (2019) Headspace conditions and ingredients can affect artefactual benzene formation in beverages. FOOD CHEMISTRY. 293, 1
- (2019) Hydrophobic deep eutectic solvents for the extraction of organic and inorganic analytes from aqueous environments. TRAC-TRENDS IN ANALYTICAL CHEMISTRY. 118, 1
- (2019) An HPLC-UV-based quantitative analytical method for Chrysanthemum morifolium: Development, validation, and application. Analytical Science and Technology. 32, 4
- (2019) Application of Deep Eutectic Solvents to Prepare Mixture Extracts of Three Long-Lived Trees with Maximized Skin-Related Bioactivities. APPLIED SCIENCES-BASEL. 9, 13
- (2019) Establishment and validation of an analytical method for quality control of health functional foods derived from Agastache rugosa. Analytical Science and Technology. 32, 3
- (2019) A comprehensive metabolomics investigation of hippocampus, serum, and feces affected by chronic fluoxetine treatment using the chronic unpredictable mild stress mouse model of depression. SCIENTIFIC REPORTS. 9, 1
단행본
- (2015) 핵심 의약품분석학. 신일북스. 공동
- (2015) 약물작용 기초이론. 군자출판사. 공동
수상/공훈
- Associate Editor of Journal of Ginseng Research (SCIE journal)
- Associate Editor of Archives of Pharmacal Research (SCIE journal)
- Editorial Board Member of Annals of Chromatography and Separation Techniques
학술회의논문
- (2021) Discovery of Sex-specific Biomarkers and Metabolic Pathways for Depression in a Subchronic Variable Stress Mouse Model. 37th International Symposium on Microscale Separations and Bioanalysis (e-MSB 2021). 미국
- (2021) Unravelling the in vitro and in vivo toxicity of deep eutectic solvents consisting of safe compounds including choline chloride. 2nd International Meeting on Deep Eutectic Systems. 포르투갈
- (2020) Metabolomic investigation of sex-specific depression in plasma and whole brain of the sub-chronic variable stress mouse model. 23rd Annual Meeting of the Korean Society for Brain and Neural Sciences. 대한민국
- (2020) Advanced biogenic synthesis of silver nanoparticles using deep eutectic solvents-based plant extracts. 2020 Fall International Convention of the Pharmaceutical Society of Korea. 대한민국
- (2020) Investigation of carvone and its eutectic mixtures as novel extraction solvents with tunable properties. 2020 Fall International Convention of the Pharmaceutical Society of Korea. 대한민국
- (2020) Discovery of biomarkers in plasma and whole brain of sex-specific depression based on non-targeted metabolomics study. The 28th Annual Meeting of the Korean Society of Applied Pharmacology. 대한민국
- (2020) Green and simple sample preparation method for trace analysis of fluoroquinolone antibiotics in surface water. 제64회 한국분석과학회 하계 학술대회. 대한민국
- (2020) Separation of chitin-glucan complex from white button mushroom (Agaricus bisporus) using deep eutectic solvents. 제64회 한국분석과학회 하계 학술대회. 대한민국
- (2020) Toxicity assessment based on non-targeted metabolomics study of natural deep eutectic solvents in in vivo mice. 제64회 한국분석과학회 하계 학술대회. 대한민국
- (2019) Benzene monitoring in beverages: revisiting analysis conditions and ingredients. 제63회 한국분석과학회 추계 학술대회. 대한민국
- (2019) Investigation of the effects of choline- and betaine- based natural deep eutectic solvents on the structure, stability and activity of lysozyme. 제63회 한국분석과학회 추계 학술대회. 대한민국
- (2019) Non-targeted metabolomics study of toxicity of natural deep eutectic solvents in in vitro cell lines and in vivo rats. 제63회 한국분석과학회 추계 학술대회. 대한민국
- (2019) In situ formed thymol-based deep eutectic solvents coupled with liquid-liquid microextraction toward simple and green sample preparation for antibiotics in surface water. 2019 Fall International Convention of the Pharmaceutical Society of Korea. 대한민국
- (2019) New approach to expanding the applicability of hydrophobic deep eutectic solvents by mixing: evaluation of their extraction capability and coverage in comparison with conventional organic extraction solvents. 2019 Fall International Convention of the Pharmaceutical Society of Korea. 대한민국
- (2019) Extractive Desulfurization with Ammonium-based Deep Eutectic Solvents: Systematic and Multifarious Consideration for the Optimal Solvent Selection. 1st International Meeting on Deep Eutectic Systems. 포르투갈
- (2019) The effects and mechanisms of deep eutectic solvents on the stability of (-)-epigallocatechin gallate. 1st International Meeting on Deep Eutectic Systems. 포르투갈
- (2019) Mixtures of menthol-based hydrophobic deep eutectic solvents: application as green solvents to extract bioactive compounds from Ginkgo biloba leaves. 제62회 한국분석과학회 춘계학술대회. 대한민국
- (2019) Investigation of the effects of different brewing conditions on Camellia sinensis infusions. 제62회 한국분석과학회 춘계학술대회. 대한민국
- (2019) Deep eutectic solvents: Green alternatives to toxic organic solvents. 2019 환경독성보건학회/환경분석학회 춘계연합학술대회. 대한민국
- (2018) Investigation of the effects of different brewing conditions on Camellia sinensis infusions. 제61회 한국분석과학회 추계 학술대회. 대한민국